Sub-acute Toxicity Studies of Acetaminophen in Sprague Dawley Rats
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منابع مشابه
Sub-acute Toxicity Studies of Acetaminophen in Wistar Rats
The aim of the present study was to evaluate the sub-acute oral toxicity of acetaminophen in Wistar rats at doses of 250 to 1000 mg/kg body weight. The following observations were noticed during the study. No mortality, no incidence of any abnormal clinical signs, no significant effect on body weight gain, no effect on the daily feed consumption, no toxicologically significant effect on the hae...
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The present study was conducted to obtain information on the effects of amitraz on reproductive and developmental parameters in rats. The test chemical was administered via the drinking water containing 0, 40, 120, and 360 ppm to male rats from 2 weeks before mating to the end of 14-day mating period and to females from 2 weeks before mating, throughout mating, gestation and up to lactational d...
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Methacrylonitrile (MeAN) is used in the preparation of plastics, elastomers, homoand copolymers and coatings (Windholz, 1983; Sax and Lewis, 1987) and as a chemical intermediate in the preparation of numerous organic chemicals (Windholz, 1983). MeAN is also used as a replacement for acrylonitrile in the manufacture of carbonated beverage containers (Cosidine, 1974) and is identified as a compon...
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Among organophosphorus pesticides, malathion is considered a relatively safe compound. Malathion, however, functions by inhibiting cholinesterase (ChE) enzymes of the nervous system in both vertebrate and invertebrate organisms. The inactivation of ChE by malathion is therefore a useful indicator of exposure. Because of the increased application of these pesticides, their entry into various env...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2014
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.b14-00066